For over 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
We are looking for a team-player Scientist with proven track of experience in histology and IHC in preclinical neuroscience to join Charles River Discovery Services site located in Kuopio, Finland.
In this position you will be leading projects that focus on identification and assessment of relevant ex vivo endpoints/outcomes of efficacy therapeutic intervention in animal models, including but not limited to,
multiple sclerosis, neurodegenerative diseases and injury-triggered animal models.
You have a strong expertise in various types of ex vivo analysis and interpretation of data derived from preclinical in vivo models. You are strong in techniques and technologies around histology/IHC and image analysis.
Other expertise in setting up and analysis of other biomolecular technologies, e.g. well plate technologies, gene expression analysis and cell population analysis are considered advantageous.
You are able to co-operate, plan, supervise and report ex vivo part of client projects together with our scientific and technical teams. Desired Scientist will be working closely with the core in vivo and imaging teams
as well as with our clients, through all stages of the research projects. In addition to client projects, scientist will be involved in R&D activities including validations of new markers and assays to support ex vivo outcome
measurements aspects of various CNS diseases.
Qualifications and Experience:
Higher education degree in biological science (MSc) with 3+ years of experience, preferably PhD degree
Pharmaceutical industry, Preclinical Contract Research Organization or academic post-doctoral experience will be an asset.
Diverse communication skills
Scientific expertise with demonstrable understanding of ex vivo neuroscience techniques and neuroimmunology as a component in CNS diseases
Hands on experience in development, optimization and validation of immunohistochemistry targets in CNS tissues
Experience in other biomolecular techniques like in vitro cell cultures, Luminex, ELISA, gene expression analysis (qPCR, QuantiGene Plex), flow cytometry will be an asset
Efficient problem solving skills, ability to coordinate, communicate and prioritize
Fluent oral and written scientific English
Track record in people management and leadership